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The high-level (HL) structure of ISO 45001 is similar to that of recent ISO standards like ISO 9001 and ISO 14001, which will make it easier to integrate it with other ISO management systems.

The ISO 45001 standard takes into account the well-being of employees in addition to work health and safety.
Planning and implementing the OHS management system depend greatly on the organizational context.

The needs and goals of the workforce are given more attention, and engagement from employees at all levels is given more weight.

The ideas of possibilities and hazards have been included. Any elements that might affect an organization's ability to accomplish the specified goals must be identified, evaluated, and addressed.

Leadership, managerial dedication, and employee participation are the pillars of the system.
Improvement and the creation of indicators are given more priority. These ought to show progress and show that objectives have been reached.

The needs for controls, change management, procurement, outsourced processes, and contractors are covered in further detail by operational control.